Colon Cancer Mutation: Prognosis/Prediction–Response
نویسندگان
چکیده
منابع مشابه
Evaluation of BRAF-V600E gene mutation in colon tissue of patients with colorectal cancer in Iran
Background: Colorectal cancer is one of the most common types of cancer and the cause of death of a large number of patients and requires investigating the causes of the disease and adopting targeted therapies. Considering the diagnostic, therapeutic, and prognostic significance of genetic markers, in the present study BRAF-V600E gene mutation was evaluated in tissue samples of colorectal cance...
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We read with great interest the recent study by Gavin and colleagues (1), who evaluated the prognostic and predictive value of DNA mismatch repair (MMR) status for oxaliplatin-containing adjuvant chemotherapy in patients with stage II and III colon cancer from National Surgical Adjuvant Breast and Bowel Project clinical trials C-07 and C-08. Of note, C-07 showed that the addition of oxaliplatin...
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The colon is a part of the large intestine and measures 1.2 meters. The glands lining the inner wall of the colon are the sites for most abnormal cell behavior such as uncontrolled cell growth, which results in polyps (non-cancerous growths) and later on in adenocarcinomas or tumors. The tumors deprive the normal surrounding tissues of nutrients and oxygen and can spread to the lymph nodes in t...
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Colorectal cancer (CRC) metastasis to the thyroid gland is rare. Here wereport a 45 yr-old man in western Iran referred to Hematology Clinic, Kermanshah city, Iran in March 2014 with complaint of exertional dyspnea, multi-nodular goiter as well as complaint of exertional dyspnea, and multi-nodular goiter. His history included a low anterior resection of rectum in 9 months ago for a high-risk st...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2013
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-13-0020